Leigh, boosted by a second win over Stalybridge in little more than a week, aim to continue their big push for safety by beating visiting Nuneaton on Saturday.
But Tuesday's victory came at a price for the Railwaymen, whose midfield kingpin Dave Ridings is now likely to be out for at least a fortnight after limping off with a pulled hamstring against Bridge.
Northwich boss Jimmy Quinn, who has been named the Conference's manager of the month for the second time this season, will receive his prize before Vics' Drill Field duel with North West neighbours Southport.
Altrincham, now 14 points adrift of UniBond premier leaders Burton, after Tuesday's 2-0 defeat at Droylsden, need nothing less than a victory against visiting Frickley to keep their fading title flame still flickering.
Dave Pace's Bloods, buoyed by that victory, will travel to Harrogate full of confidence for their Chairman's Cup semi-final date with the first division leaders.
Trafford, seeking to become only the second club to have won all three UniBond knockout competitions, visit Accrington in the Challenge Cup's last-four, while Ashton United, boosted by a 2-1 midweek win over Radcliffe, host Barrow in the President's Cup semis.
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