The French World Cup star has signed a new two-year deal with the club and follows in the wake of Andrew Sheridan, Sebastien Chabal and Lee Thomas, who have all penned new contracts in the last two months.
Bruno joined Sale in 2004 and was a pivotal member of the side that beat Pau in the European Challenge Cup final in 2005.
Director of rugby Philippe Saint Andre said: "Sebastien is one of the most consistent players in my team. He always gives 100 per cent and never takes a backward step.
"He is very settled living in the Manchester area and is looking to finish his career playing for us. It's great news for the club."
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