Devlin has been signed on loan from Widnes Vikings to provide cover at centre following injuries to both Jos Baxendell and Dan Harris.
Sale's starting XV is the same as the one which defeated Leicester at Welford Road last weekend, with Chris Mayor keeping his place in the centre.
Head coach Jim Mallinder said: "Wasps won the title last season and are always a very tough side to play against.
"It's good to have Paul back with us, and we are grateful to Widnes and coach Neil Kelly for agreeing to let him join us."
SALE: Going, Cueto, Bond, Mayor, Hanley, van Straaten, Walshe, Sheridan, Titterell, Turner, Fullarton, Schofield, Sanderson (c), Pinkerton, Jones. Reps: Yates, Cairns, Stewart, Lund, Wigglesworth, Devlin, Hoyle.
Prop Jason Cundick makes a welcome return for Manchester as the bottom-placed club in National One prepare to take on leaders Worcester. Neil Fletcher takes his place in the second row after joining the club on loan from Pertemps Bees (formerly Birmingham/Solihull).
James Bramhall is still out with concussion so veteran Anton Hanson remains at scrum-half, with former Sale Jet Stuart Brown at fly-half.
Director of Rugby Ian Geary said: "Worcester will be out to score as many points against us as possible but we always seem to do well against the bigger clubs because the pressure is off us."
Orrell return to league action tomorrow when they take on Bristol Shoguns at Edge Hall Road, kick off 2pm.
Following their win against London Welsh in the third round of the Powergen Cup last week, Orrell will be looking for a strong performance.
Scott Barrow reverts to his favoured full-back slot which allows Leigh Hinton to move out to the right wing with Simon Haughton back on the left.
Wade Kelly also returns to action at inside centre with Rodd Penney outside.
In the pack Simon Emms returns at loose head with former England hooker Neil McCarthy back to face his old club.
Sedgley coach Tim Fourie has the luxury of naming an unchanged starting XV for his side's clash against Rosslyn Park, as they look to continue their sizzling start to the National Two campaign.
Macclesfield face a tough test as they travel to fallen giants Waterloo in National Three North. They are without lock Jeremy Bostock, so Ollie Hewitt teams up with Tim Kerr in the second row, with player coach Dave Muckalt in the back row.
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