WIGAN captain Arjan de Zeeuw could return to the side for the Premiership clash with United.

De Zeeuw missed Saturday’s 1-0 defeat at Chelsea with a knee injury, the first league game this season in which the centre-back had sat on the sidelines.

With Wigan in a spell of four games in 11 days, manager Paul Jewell may again make other changes as he attempts to keep his team fresh.

Meanwhile, Mikael Silvestre is a doubt for the Reds.

According to manager Sir Alex Ferguson, the French defender picked up a "slight knock" during Sunday's draw with Everton, so Wes Brown is standing by for a recall.

Top scorer Ruud van Nistelrooy also returns from suspension, so Louis Saha is likely to find himself back on the substitutes' bench.

Manchester United (from): Van der Sar, Howard, Neville, Bardsley, Ferdinand, Silvestre, Brown, O'Shea, Richardson, Ronaldo, Scholes, Smith, Fletcher, Park, Giggs, Rooney, Van Nistelrooy, Saha, Rossi.

Wigan Athletic (from): Pollitt, Chimbonda, McMillan, Jackson, Henchoz, Camara, Johansson, De Zeeuw, Kavanagh, Mahon, Francis, Taylor, Teale, Bullard, Baines, McCulloch, Roberts, Skoko, Connolly, Wright, Walsh.

Key opponent: Wayne Rooney - One of the world's best players and unstoppable on his day

Prediction: United 2 Wigan 0

Agree with the prediction? Have your say.

You can get 16/1 on Wigan to win 1-0 with Betfred. For this and more odds, click here.

Tweet