Keith Hill's men have hit top form in the last couple of weeks and travel to London on the back of victories over Chester, Aldershot and Notts County.
Brentford sit fourth in the League Two table despite a 3-0 loss at Chester in midweek.
They are one point ahead of Dale and are sure to provide a stern test.
"They came unstuck on Tuesday but they have not turned into a bad team overnight," said Dale assistant boss Dave Flitcroft.
Will Buckley is pushing hard for a place in Dale's starting line up after coming off the bench on Tuesday.
Brentford league form: DDWDL
Rochdale league form: DDWWW
Key opponent: Glenn Poole - Spent time with Dale last year and has an eye for goal
Prediction: Brentford 1 Dale 1 - The Bees haven't been in the best form but are still tough to beat at home
You can get 17/2 on Dale winning 1-0 with Betfred. For this and more odds, click here.
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