The Dutchman will start at Villa Park as he keeps up his record of playing in every Premier League game this year.
But that comes after two lengthy absences and a period of compassionate leave just before Christmas when his wife Annemarie suffered a brain haemorrhage.
Thankfully, his wife has recovered sufficiently well for Van der Sar to resume his career at Old Trafford, bringing a sense of stability to a side that had been struggling for consistent results.
"It feels really good to be back playing," he said.
"It has been a stop-start season for me and you miss your weekly routine of training and games.
"But if feels great to be back in the swing of things and playing for United again."
The 39-year-old will be part of the old guard determined to keep up their fine form as they bid for a record fourth title.
Veteran duo Paul Scholes and Ryan Giggs are set for recalls after not even making the bench for Saturday's 5-0 demolition of Portsmouth.
Rio Ferdinand is suspended, while Nemanja Vidic has an outside chance of being involved for the first time this year after suffering a nerve problem in his leg last month.
For Villa, Emile Heskey is struggling to be fit after suffering a groin injury in their 0-0 draw at Spurs at the weekend while Stephen Warnock is out with an ankle problem.
United (from): Van der Sar, Kuszczak, Neville, Brown, Rafael, De Laet, Vidic, Evans, Evra, Fabio, Park, Nani, Valencia, Carrick, Scholes, Fletcher, Gibson, Anderson, Giggs, Rooney, Owen, Berbatov, Diouf.
Villa (from): Friedel, Guzan, Beye, Cuellar, Collins, Dunne, L Young, A Young, Petrov, Milner, Downing, Delph, Agbonlahor, Carew, Heskey, Delfouneso, Sidwell, Davies, Clark.
United league form: WWWLW
Villa league form: DWDDLL
Key opponent: Gabriel Agbonlahor – Scored the winner at Old Trafford
Prediction: Villa 1 United 1 - The Reds may be forced to settle for a point against a well-organised side
Agree with the prediction? Have your say.
Click here for all the latest odds from Betfred.
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Showing comments 1 to 25 and replies | View All
Redraw, Belfast (09/02/2010 at 14:05)
Doc Savage (09/02/2010 at 14:10)
Valencia Brown Evans Evra,
Nani Scholes Fletcher Carrick Giggs,
Rooney
Fonzy, London (09/02/2010 at 14:14)
jordy, Middleton (09/02/2010 at 14:26)
Ibrahim Bobat (09/02/2010 at 14:28)
krutt (09/02/2010 at 14:31)
My team would be - VDS, Nev, Brown, Vidic (If fit if not Evans) Evra, Valencia, Fletcher, Carrick, Scholes, Nani & Rooney. Playing 4 5 1.
ENGINEER, Heywood (09/02/2010 at 14:33)
Van Da Saar
Depending who is fit.
Fabio/Brown Brown/Vidic Evans Evra
Nani Fletcher Carrick Scholes Park
Rooney
Subs: Kushak, Valencia, Diouf, Berbatov, Fabio/Gibson
No Anderson as he seems to have fallen out with Fergy.
jordy, Middleton (09/02/2010 at 14:39)
Drago 34 (09/02/2010 at 14:40)
.....................Van Der Sar....................
Rafael..........Vidic..........Evans..........Evra
........Carrick.......Fletcher.......Scholes.......
Valencia..............Rooney..................Nani
Subs: Kuszackz, Brown, Anderson, Giggs, Berbatov, Diouf, Owen
If we go 4-4-2 then i would play...
.....................Van Der Sar....................
Rafael..........Vidic..........Evans..........Evra
Valencia......Fletcher........Carrick........Nani
................Rooney........Berbatov............
Subs: Kuszackz, Brown, Anderson, Giggs, Park, Diouf, Owen
What ever happens just play ALL the in form players and be proffesional, disiplined and clinical.
Gilly, Belgium (09/02/2010 at 14:48)
We have to win as many as we can to stay in the chase !
Play a good team please SAF !
jordy, Middleton (09/02/2010 at 14:54)
Paddy Evra's Captains Armband, Manchester M1!! (09/02/2010 at 15:01)
United's latest League Form as per M.E.N - WWWLW
No it ain't!
We are top of the Form League having the current overall record from the last 6 games - W D W W W W - total 16 out of 18 points.
Current home form - L W W W W W - 15 out of 18 points.
Current away form - W W L W D W - 13 out of 18 points.
I hope this isn't the sign of the times now that the M.E.N is now owned by Mirror Trinity (LIVERPOOL ECHO)??!!
A sad day for all Mancs that....:0(
Ben'sDad, WA4 (09/02/2010 at 15:06)
Balders!, W3106, Tier2 (09/02/2010 at 15:37)
In addition, if vidic plays, then Wes has to be RB. The rest will sort itself.
Alias Smith, over the moon (09/02/2010 at 15:49)
Doc, hopeful of seeing Valencia at right back much?
Redraw, Belfast (09/02/2010 at 15:58)
To Fonzy, London
I agree with Berbatov but certain games we cant play him and Villa might be one of those games.
Brora boy, Highlands (09/02/2010 at 17:54)
I saw Duncan Edwards play, Walton Le Dale (09/02/2010 at 20:16)
I cannot even guess what team SAF puts out, but I trust his judgement implicitly!
I forecast a 2-0 win.
Bigmouth strikes again, Manchester (09/02/2010 at 21:02)
Brown Vidic Evans Evra
Nani Fletcher Scholes Giggs
Rooney Berbatov
Doc Savage (09/02/2010 at 21:13)
Effectively I am trying to get Nani and Valencia into the same team. Although to achieve this, I would also be keen to try Nani as the second-striker behind Rooney.
Alias Smith, over the moon (09/02/2010 at 21:59)
There is more of a chance that he might use Valencia in CM but he's shown no inclination to do so as yet.
Mike Summerbee's socks (09/02/2010 at 22:56)
Doc Savage (09/02/2010 at 23:53)
9/02/2010 at 21:59
When these innovations happen, remember you heard it here first.
John Terry's Magic Boots Oops (09/02/2010 at 23:59)
I am with most and think SAF will go 4-5-1
VDS
Rafael-Brown-Vidic-Evra
Nani-Carrick-Scholes-Fletcher-Giggs
Rooney all alone.
Unfortunately this will leave us too slow on the counter attack on the left....but money is on this lineup as Fergie tries to get his experience in.
Hopefully we can get one by early or it could be a long day.
chew, Grenada (10/02/2010 at 00:42)
My view is that unless he can effectively change his playing style to blend with the United style he should be off-loaded!
Score line against Villa;United2 Villa 0.