Evans picked up a calf injury on international duty with Northern Ireland a fortnight ago, while O'Shea suffered an thigh injury during the Republic of Ireland's controversial World Cup play-off defeat to France.
Patrice Evra is set to return, along with Wayne Rooney, Dimitar Berbatov, Edwin van der Sar and Darren Fletcher as United look to close the gap on leaders Chelsea to two points ahead of the Londoners' meeting with Arsenal.
New Portsmouth boss Avram Grant, who has taken charge of training for the first time today, will have the backing of the notoriously vociferous Fratton Park fans.
The former Chelsea manager replaces Paul Hart, who was sacked on Tuesday with the club rooted to the foot of the Premier League with only seven points from 13 games.
Grant's first match is against a familiar foe in United. The Israeli will no doubt be hoping to turn the tables on Sir Alex Ferguson's side as his last game in charge of Chelsea was the Champions League final of 2008.
It ended in agony for Grant with his team losing on penalties in Moscow.
Tweet


Showing comments 1 to 23 and replies | View All
Gerry, Glastonbury (27/11/2009 at 13:46)
VDS, Fab / Nev, Wes, Vid & Patrice. Valencia Scholes, Fletch & Giggs. Rooney. Berb.
Expect some fireworks!
ENGINEER, Heywood (27/11/2009 at 14:16)
Monkey tennis?, yes please (27/11/2009 at 14:31)
And i want some of that friday feeling that Gerry's got, go get 'em big man, sounds like Mrs Gerry is in for a good weekend.
Gilly, Belgium (27/11/2009 at 14:53)
Seamus, Vanisle,ex-Stretford (27/11/2009 at 15:11)
steve wilson (27/11/2009 at 15:19)
bobbydazzler (27/11/2009 at 15:20)
neal 07, south stand lower (27/11/2009 at 15:40)
Lets give Pompey an early Christmas stuffing and kick on, watching the old men of Chelski drop points at the Gooners!!!
0-4 to the Champions!!! Rooney hat trick!!!
the artist, capital of trophies (27/11/2009 at 15:53)
Neville................Brown.................Vidic............Evra
Valencia.............Fletcher...............Scholes..........Giggs
.....................Berbatov................Rooney...............
SUBS: Foster, Rafael, DeLaet, Park, Carrick, Anderson, Owen
P.S. my take on the Besiktas match: I would have played the exact XI as SAF and I would do so again vs Wolfsburg. Why? Because it really doesn't make that much difference finishing top or second......
Possible opponents if finishing top: Real Madrid, Inter, Juventus, Fiorentina, Porto, Stuttgart, Olympiakos.
Possible opponents if finshing second: Barcelona, Seville, Milan, Bordeaux, Lyon.
There are both tough and not-so-tough (on paper) teams in both scenarios,so....
As for the second leg at home, we've made a pig's dinner of that 'advantage' before so....
Alias Smith, over the moon (27/11/2009 at 16:05)
paul salmon (27/11/2009 at 16:19)
This is the period where we tend to kick on, stringing together a run of wins. Anything less than maximum points from now until the new year will not be good enough. We're good enough to achieve that, especially considering Rooney's due another run of goals.
Paul, Whalley Range
Scholsey passed me the ball..., England (27/11/2009 at 17:32)
World-wide-United, Not-in-wasteland (27/11/2009 at 18:55)
neville brown vidic evra
valencia fletcher carrick nani
berbatov
roony
giggs anderson obertan in the subs
Drago 34 (27/11/2009 at 18:55)
Neville..........Vidic..........Brown..........Evra
Valencia.......Fletcher.......Carrick.........Giggs
.................Rooney.......Berbatov
Subs: Foster, Rafael, De Laet, Scholes, Obertan, Park, Owen
Al (27/11/2009 at 19:26)
Viva Fergie. Manchester is RED, Mancunia (27/11/2009 at 19:42)
palomablanca, manchester (27/11/2009 at 19:45)
DC, New York (27/11/2009 at 20:05)
DUB RED, CLONDALKIN (27/11/2009 at 21:07)
Seamus, Vanisle,ex-Stretford (27/11/2009 at 22:00)
Link, Birmingham (28/11/2009 at 00:13)
Pritesh Mistry (28/11/2009 at 06:57)
Valencia, fletcher, carrick, giggs,
Rooney Owen
I just read an interview wherein Rio was talking about the time before Chelsea United Champions league final in 2008. Its amazing & a must read for all United fans..
www.goonersanddevils.com/man_utd.html
Raju, Katmandu (28/11/2009 at 17:30)
Who won 4-1 while the world's richest club drew again? Tick tock, tick and tock. Or rather, its ding dong, ding and dong. Parkie's better than Bobinho. He sells more credit cards too. And he's got more medals than your trophy room. Ding Dong!
7 in a row for you guys, draws that is, and 4 in a row for the red side, of what? PL Cups that is.