Carlos Tevez may be among the star names that do take part after sitting out Sunday's Manchester derby triumph at Eastlands.
Cristiano Ronaldo is suspended but he would not have played anyway, while Ben Foster is likely to be handed the goalkeeping slot.
Defender Martin Olsson comes back into contention for Blackburn.
Olsson sat out Saturday’s 3-2 loss at Portsmouth through suspension following his dismissal at Spurs the previous week.
Keith Andrews is ineligible, whilst Vince Grella (calf), David Dunn (Achilles) and Steven Reid (knee) remain sidelined through injury.
Manchester United (from): Foster, Kuszczak, Rafael, Evans, Cleverley, Neville, Chester, Vidic, O'Shea, Nani, Park, Fletcher, Anderson, Possebon, Gibson, Giggs, Tevez, Welbeck, Manucho.
Blackburn Rovers (from): Robinson, Brown, Simpson, Ooijer, Samba, Nelsen, Emerton, Khizanishvili, Warnock, Mokoena, Olsson, Tugay, Treacy, Pedersen, Roberts, Derbyshire, Villanueva, Santa Cruz, Fowler, McCarthy.
Which team would you send out? Have your say.
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Gerry, Glastonbury (02/12/2008 at 10:16)
the artist formerly known as Saha Rocks, pundit land (02/12/2008 at 11:04)
Foster; Rafael, Neville, Evans, O'Shea; Gibson, Fletcher, Anderson, Nani; Tevez, Giggs.
SUBS: Kuszczak, Vidic, Park, Possebon, Welbeck, Manucho, Cleverley
Enterprise (02/12/2008 at 11:11)
Dan (02/12/2008 at 11:18)
TAKIN , strasbourg france (02/12/2008 at 11:21)
foster vidic evans rafael oshea anderson possebon fletcher nani tevez wellbeck
kuzack neville evra carrick gibson park manoucho
Solskjaer20Legend, Epsomville (02/12/2008 at 12:08)
Hopefully Neville will get a game and O'shea and Rafael will get rested for Sunderland!!
Manucho and Welbeck to play a decent portion of the game too.
Angry Bogan, Oz (02/12/2008 at 12:57)
My team: Foster, Rafael, Evans, Chester, Gibson, Fletcher, Anderson, Possebon, Tevez, Welbeck, Manucho (60m sub for Welbeck).
Giggs showed he can't match the pace; O'Shea is Mr. reliable rather then inspirational. Give the 'kids' a chance.
Eric7, Salford (02/12/2008 at 13:31)
Col, Ontario., Canada (02/12/2008 at 13:37)
Haakon (02/12/2008 at 13:56)
My guess at the lineup; Foster - Neville Evans Chester (or Vida) O'shea - Nani Anderson Possebon (or Gibson) Giggs - Tevez Manucho (or Welbeck)
TBH - I can see that team beating Blackburn.
belfastboy, pickering, canada (02/12/2008 at 15:30)
I would play a pretty strong team that certainly wouldnt include gary N, he needs to play his career out in the reserves
my team would have evans, the brazilian kids and vidic at the back, fletch, nani, park and giggs in the middle with rooney and tevez up front
rooney particularly needs to get sharp and tevez needs to get his confidence back
remember Its sunderland next in the EPL, likely 3 points wrapped up without a sweat on the weekend
Cyprus Red, Cyprus (02/12/2008 at 16:02)
Django, Hampshire (02/12/2008 at 16:03)
belfastboy, pickering, canada (02/12/2008 at 16:32)
still feel we need to get a strong team out and get to the final, but I do agree with playing some of the young kids
Enterprise (02/12/2008 at 16:43)
No-one denies that Ryan Giggs was a good player once. That was some years ago, however. Now he is so poor, in fact dire is the appropriate word. He must know this, losing the ball at every opportunity. How can anyone have respect for him continuing to draw a large pay packet and keeping younger talent out of the team? The honourable thing would have been to quit after receiving his cup winners medal.
Pepe (02/12/2008 at 18:34)
Pepe (02/12/2008 at 19:15)
bobbyc, Manchester (02/12/2008 at 20:55)
at Eastlands.
Robinho must be thinking "what have I done"
getting involved with these losers?
Alias Smith, over the moon (02/12/2008 at 22:25)
Foster, Rafael, Evans, Vidic, O'Shea, Nani, Anderson, Possebon, Gibson, Tevez, Welbeck.
It looks like it's us or Spurs for the cup and I would fancy that Harry will play his strongest team no matter who he comes up against so you've got to make Spurs favourite.
keithmat (02/12/2008 at 23:02)
Lets loan some players to Keane and Ince and Hughes and Bruce after Xmas try and keep all the United managers in the Premier League.
david the red, toronto (03/12/2008 at 05:15)
Gerry, Glastonbury (03/12/2008 at 08:36)
This is a very tricky game for Spurs and it wouldn't surprise me in the slightest if they get knocked out.
That would put three Championship sides in the last four. I think Ince would be bananas to ignore that and play a weakened side. For them it's the best opportunity they'll have of winning a trophy this season.
chris, oxford (03/12/2008 at 09:30)
bobbydazzler (03/12/2008 at 11:19)
Alias Smith, over the moon (03/12/2008 at 12:41)
chris, the papers think that Ince will put out a strong side (well, strong for Blackburn). Could make for a very interesting game if so - a big test for our youngsters.