The Reds will fly to Africa on Thursday afternoon with their first match against Kaizer Chiefs at the Newlands Stadium, Cape Town, on Saturday.
Ferguson's side then face Orlando Pirates in Durban on Tuesday July 22, before playing one of the two South Africa sides again in the Vodacom Challenge final at Loftus Stadium, Tshwane - previously called Pretoria - on Saturday July 26.
In the same pre-season tournament two years ago United lost to Kaizer Chiefs on penalties in the final.
There will be a hectic end to the tour with a friendly the following night in Abuja, Nigeria, against Portsmouth on the way back.
Ferguson told MUTV: "The games in South Africa aren't easy games. It's a good, competitive level, so that should bring us on a good deal.
"I think by the time we get to the start of the season we'll be really ready."
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A level head - you decide (15/07/2008 at 15:47)
How quickly does a player lose optimum fitness levels. People talk as though players have forgotten everything they were doing just 3 months ago, whatever club they are at.