The former Real Madrid striker suffered a recurrence of an ankle injury in the 3-1 defeat by Racing Santander in the UEFA Cup tonight.
Robinho made a surprise start for City but played only 45 minutes as he was struggling with the problem.
Manager Mark Hughes said: “Robinho was not able to continue so he is a big doubt for the weekend. It it his ankle again.
“We are staying here overnight so we will check everyone in the morning.
“He has made a great impression on everyone in Manchester, scoring eight goals in the Premier League. We are delighted with his impact.
“In the last three games he has been struggling with an injury and that was a concern to him tonight. We are pleased with what he has produced. ”
Even though City's campaign in the group stages ended in disappointment, they advance to the knockout stages in top spot.
That means they will face a third-placed side in one of the other groups when the draw is made tomorrow.
Goals from Jonathan Pereira and Oscar Serrano put Santander in the driving seat before half-time.
Juan Valera extended their lead before Felipe Caicedo scored a late consolation goal for City after stepping off the bench.
Hughes, who made wholesale changes to his side, said: “Ideally we would have preferred to have won the game but credit to Racing, they are a good team.
“Their motivation was to try and get into the next round. We had already qualified so that might have taken a little bit of edge out of our game.
“We made changes as we wanted to give the likes of Shaun Wright-Phillips, Stephen Ireland and Vincent Kompany a little bit of a rest.
“I think that was important given the number of games coming up. They are key players for us.
“In the second half we just needed to steady ourselves and we did that. We got more games into some of the players who have not had a lot of football.
“Gelson (Fernandes) got 90 minutes which is important while Caicedo has come on and made an impression. We have to take the positives out of the game.
“We have topped the group and that was the order of the day. We are grateful for that.”
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Dunneymonster (18/12/2008 at 23:26)