Andrew, who hit 57 against Southport, has missed the last two games due to football commitments with Northwich Vics.
Relegated Worsley are bottom of the table, but skipper Naill Howarth is hoping for a change in fortunes.
Leigh, runners-up last season, open their ECB Premier League campaign at home to Northop Hall.
Saturday: Leigh v Northop Hall, Ormskirk v Wigan, Newton-le-Willows v Maghull, Bootle v New Brighton, Northern v Huyton, Wallasey v Lytham. Div 1: Fleetwood Hesketh v Sefton Park, Haydock v Liverpool, Highfield v Hightown, Orrell RT v Worsley, St Helens v Caldy, St Helens Recs v Colwyn Bay, Southport v Formby.
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