Up to 30 firefighters tackled the blaze at the old Empress Building, Oldham Road.
The first crews from Manchester Central and Philips Park discovered the two-storey building well alight with flames shooting through the roof.
They immediately called for back up and were clear of the building when the front collapsed.
Debris was scattered across two lanes of Oldham Road, which was closed in the direction of Manchester to Oldham.
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Steve Lynch, Sale, Manchester (18/06/2006 at 23:42)
Ps wonder how long it will be till the old ODEON burns down or is demolished!