Those behind the Stuff Your Loans campaign say it has been set up "in sheer desperation" amid concerns at mounting graduate debt.
And their anonymous internet-based campaign is also appealing to sixth-formers not to apply to university or boycott those in the so-called Russell Group, including the University of Manchester, which are perceived as keen to increase tuition fees further.
One Manchester graduate, claiming to be involved in the Stuff Your Loans campaign, says he believes he was misled into going to university with the prospect of a well-paid job at the end.
Misled
He says he has accumulated £23,000 of debt over the past three years, has returned to live with his parents, and is working in a fast food outlet, where he earns £6 an hour. He hopes the campaign will lead the government to rethink its policies.
"I have just graduated from the University of Manchester and I am phenomenally in debt," he said. "I feel very, very angry and let down.
"The money you get doesn't cover your expenses. You have to borrow to try to survive. If I could afford to pay it back, I wouldn't."
The website says: "Once you have your degree, then we ask that you consider a refusal to repay your loans. If you are reading for a professional degree such as medicine, pharmacy, dentistry etc, do not refuse to repay your loans until you are fully registered with your regulatory body.
"Your universities cannot do anything at this point. They cannot take your qualifications off you after you have graduated."
Higher Education Minister Bill Rammell slammed the campaign as "irresponsible", adding: "We advise people to go to trusted sites such as our own www.dfes.gov.uk/studentsupport."
Meanwhile, the Student Loans Company has pointed out that anyone defaulting on payments would face legal sanctions. The University of Manchester declined to comment. Tweet

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Yes it's wrong that students have to pay. They would be given money if they were on the dole but because they are trying to be educated which will benefit everyone in society they are being left to struggle and spending increasing time working and less time studying.
Student loans came in because there was a target to get more people into higher education. That increased the costs and the students were forced to bear this themselves.
Yes students will benefit financially if they earn more once they graduate, but as income tax and National Insurance is based on a percentage system so will the government.
If the government tightened up their length of residency requirements it would also help funding so that UK based students get help and not those from other EU countries.
As a graduate of two years, my income has increased steadily since leaving the University of Manchester and I don't mind paying back loans for a brilliant three years in higher education. My experience gave me skills, ambition, drive and a sense of responsibility and the value of this time is much higher than my real 'debt'. Students can complain, but a university education is still a privelege and like most things in life, it's not handed to you on a plate (nor should it be) and it costs money. More students from poorer backgrounds can afford to have access to world class facilities and as a result of tuition fees, facilities are only going to improve. As long as they are realistic and subsidised, tuition fees can only be a good thing. Campaigns like this are just immature cries for help from people who don't want to act like adults.
Refuse to pay? The do gooders that read this and feel sorry for the poor cop-out students having all this debt need to go walk along wilmslow road in fallowfield any night of the week. The bars are fully of students peeing their grants up the walls. And too think after all them years in education, sponging, scrimping, eating noodles, they get to work in a fast food store for B#6 an hour. What a joke, students know that theyre going to get into debt. Sleep in the bed you made.
But always manage to find money for booze and takeaways! Get real
I would like to thank you for publishing this article. All I would ask is that people are aware of the site www.stuffyourloans.co.uk