Three people were taken to hospital and junction 4 clockwise was closed while emergency services dealt with the incident.
The collision involved a VW Golf, a black VW Bora and a Vauxhall Vectra all travelling clockwise on the motorway.
The driver of the Bora had to be cut from his wrecked car by firemen.
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There has been another accident at Trafford Boulevard so not sure how bad or what it's going to be like.